Theodorus van Es Professor Rutgers University Dept. of Biochemistry & Microbiology 129 Lipman Hall School of Env & Biol Sciences New Brunswick. NJ 08903-0231 (732) 932-8508 FAX - 8965 vanes@aesop.rutgers.edu

Carbohydrate chemistry and biochemistry. the application of modified glycosidases in the synthesis of glycosides. synthetic applications of modified enzymes in organic solvent media

Research interests are in i) carbohydrate chemistry and biochemistry e.g.. the application of modified glycosidases in the synthesis of glycosides. ii) synthetic applications of modified enzymes in organic solvent media. iii) non-immunogenic enzymes.

Selected Publications

van Es, T., Staskun, B. Fernandes, M. (2007) Preparation, X-ray structure and propylaminolysis of 7.7-Dichloro-5,7 -dihydro-theiro[3,4] pyriden-5-one. J. Chem. Res. 376-376.

van Es, T., Staskun, B. Piggot, A. (2006) The Synthesis of 4-Ethyl-2-propyl-3-substituted-pyrrolo [3,4-b] quinoline-1,9-dione derivatives from 3,3,-Dichloro-4-ethyl-thien [3,4-b] quinoline-1,9-dione and Propylamine. S.Afr. J. Chem. 59: 101-108.

Carlton L. Staskun B. van Es T. (2006) A nitrogen-15 NMR study of hydrogen bonding in 1-alkyl-4-imino-1,4-dihydro-3-quinolinecarboxylic acids and related compounds. Magn Reson Chem. 44(5):510-4.

Van Es. T. and Staskun. B. and MA Fernandes. S. (2003). Production of q-thioxo-2,3,4,9-tetrahyelro-pryolo [3,4-b] quinoline -1-ore derivatives from the aminolysii of 3. 3. 9-tricheoroa 3 H-theiro[3,9-b] quinoline -1-ore. S.Afr. Journal Chem. 56:30-33.

Van Es. T. and Staskun. B. (2003). Chlorine and sulphur-substitued Pyrrolo [3,4-b] quinoline and related derivatives arising from aminolysis of 3,3,9-Trichlorothieno [3,4-b]quinolin -1[3,4. ]-one. S. Afr. J. Chem. 56:40-46.

Van Es. T. and Staskun,B. (2002). Internet version. Alkyl-1,4. -dihydro-4-iminoquinoline-3-carboxylic acds? Synthesis. structure and properties. S. Afr. J. Chem. 55:13-33.

Levendis. D.C.. Moffitt. J.. Staskun B. and van Es. T. (1999) Thionyl chloride-induced conversion of 1-ethyl-1,4-dihydro2-methyl-4-oxoquinoline-3-carboxylic acids to highly functionalised thieno [3,4-b] quinoline derivative. J. Chem. Res. 614-615.

Staskun. B. and van Es. T. (1998). 1-Alkyl-1,4-dihydro-4-imino-3quinoline carboxylate. Part 1. General synthesis. S.A.J. Chem. 51:92-99.

Van Es. T.. and Staskun. B. (1998). Rearrangements and decarboxylations accompanying the hydrolysis of 1-alkyl-4-alkylimino-1,4-dihydro-2-methyl-3-=quinoline carboxylate and related compounds. S.A.J.Chem. 51:21.

Van Es. T. and Staskun. B. (1998) Activation of the 4-oxo function in 1-alkyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids with thionyl chloride. J. Chem. Soc.. Perkin Trans. I. 3137-3138.